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Article

Nasal IL-4(+)CXCR5(+)CD4(+) T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps.

The Journal of allergy and clinical immunology - 1 Feb 2016

Zhang Ya-Na, Song Jia, Wang Hai, Wang Heng, Zeng Ming, Zhai Guan-Ting, Ma Jin, Li Zhi-Yong, Liao Bo, Wang Bao-Feng, Zhen Zhen, Wang Nan, Cao Ping-Ping, Lin Peng, Ning Qin, Liu Zheng

Abstract excerpt

BACKGROUND: Locally produced IgE contributes to the initiation and development of eosinophilic inflammation in eosinophilic nasal polyps independent of systemic atopy. However, whether CXCR5(+)CD4(+) T follicular helper (TFH) cells are involved in local IgE production at mucosal sites remains une...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 26329514
DOI: 10.1016/j.jaci.2015.07.025

Genes

CXCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26329514-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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