Article
An Improved PCR-RFLP Assay for the Detection of a Polymorphism of PLIN1 Gene.
Clinical laboratory - 1 Jan 2016
Duan Xiaoran, Li Chunyang, Wang Tuanwei, Feng Xiaolei, Cui Liuxin, Yao Wu, Wang Wei
Abstract excerpt
BACKGROUND: In recent research, it has been shown that there have been variants of rs894160 within the PLINI gene which have been associated with obesity, type 2 diabetes, and other diseases. But the isoschizomers such as the Mn1I enzyme required for the detection of this polymorphism are expensive. METHODS: The study used an improved PCR-RFLP method with mismatched base for detection of the single nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
