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DNM1L-mediated fission governs mitophagy & mitochondrial biogenesis during myogenic differentiation

1 Apr 2025

Abstract excerpt

BACKGROUND: Remodeling of the mitochondrial network is implicated in myogenesis. Remodeling processes including mitochondrial fission, mitophagy, and biogenesis are important as they finetune the mitochondrial network to meet the increased energetic demand of myotubes. Evidence suggests that mitochondrial fission governs other mitochondrial remodeling processes; however, this relationship is unclear in the...

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PMID: 40170111
DOI: 10.1186/s12964-025-02142-x

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