Genetic biomarkers for the risk of seizures in long QT syndrome.

doi:10.1212/WNL.0000000000003056

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Article

Genetic biomarkers for the risk of seizures in long QT syndrome.

Neurology - 18 Oct 2016

Auerbach David S, McNitt Scott, Gross Robert A, Zareba Wojciech, Dirksen Robert T, Moss Arthur J

Abstract excerpt

OBJECTIVES: The coprevalence, severity, and biomarkers for seizures and arrhythmias in long QT syndrome (LQTS) remain incompletely understood. METHODS: Using the Rochester-based LQTS Registry, this study included large cohorts of LQTS1-3 participants (LQTS+, n = 965) and those without a LQTS mutation (LQTS-, n = 936). RESULTS: Compared to LQTS- participants, there was a higher prevalence of LQTS1, LQTS2, and...

Topics

Adult
Cohort Studies
ERG1 Potassium Channel
Female
Follow-Up Studies
Genetic Markers
Genetic Predisposition to Disease
Humans
KCNQ1 Potassium Channel
Long QT Syndrome
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Prevalence

Registries

Risk

Risk Factors

Seizures

Severity of Illness Index

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Identifiers

PMID: 27466471
DOI: 10.1212/WNL.0000000000003056
PMCID: PMC5085072

Genes

KCNH2

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