Article
Diagnosis, management and therapeutic strategies for congenital long QT syndrome.
Heart (British Cardiac Society) - 1 Mar 2022
Wilde Arthur A M, Amin Ahmad S, Postema Pieter G
Abstract excerpt
Congenital long QT syndrome (LQTS) is characterised by heart rate corrected QT interval prolongation and life-threatening arrhythmias, leading to syncope and sudden death. Variations in genes encoding for cardiac ion channels, accessory ion channel subunits or proteins modulating the function of the ion channel have been identified as disease-causing mutations in up to 75% of all LQTS cases. Based on the...
Topics
- Arrhythmias, Cardiac
- Electrocardiography
- Genetic Testing
- Genotype
- Humans
- Ion Channels
- Long QT Syndrome
- Mutation
- Phenotype