Article
High-resolution Melting PCR Analysis for Genotyping Lys109Arg and Gln223Arg in Patients with Renal Cell Carcinoma.
Annals of clinical and laboratory science - 1 Jul 2016
Zhang Hai-Ping, Zou Jian, Yin Ying, Ruan Jun, Xu Zhuo-Qun, Yang Shu-Dong, Mu Hui-Jun
Abstract excerpt
Although several studies have documented the role of leptin receptor gene polymorphisms in cancers, the association between leptin receptor gene polymorphisms and renal cell carcinoma (RCC) remains unknown. The aim of this study was to develop a high-resolution melting (HRM) approach for genotyping single nucleotide polymorphisms of leptin receptor gene on the LightCycler 480, and to explore the relation between...
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