Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Latency for cytomegalovirus impacts T cell ageing significantly in elderly end-stage renal disease patients.

Clinical and experimental immunology - 1 Nov 2016

Huang L, Langerak A W, Baan C C, Litjens N H R, Betjes M G H

Abstract excerpt

The number of elderly patients with end-stage renal disease (ESRD) has increased significantly during the last decade. Elderly ESRD patients are vulnerable to infectious complications because of an aged immune system. Additional immunological ageing effects may be derived from the uraemic environment and cytomegalovirus (CMV) latency. Elderly patients may be affected by these factors in particular, but data in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Viral
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytomegalovirus

Share to Cytomegalovirus Infections

Share to Kidney Failure, Chronic

Share to Lymphocyte Count

Share to T-Lymphocyte Subsets

Share to Virus Latency

Source

Open in PubMed Open full text

Identifiers

PMID: 27460884
DOI: 10.1111/cei.12846
PMCID: PMC5054567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Latency for cytomegalovirus impacts T cell ageing significantly in elderly end-stage renal disease patients.PMID 27460884Read ↗

Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses.Semantic proximity Read ↗

Association of Premature Immune Aging and Cytomegalovirus After Solid Organ TransplantSemantic proximity Read ↗

T Cell Replicative Senescence in Human AgingSemantic proximity Read ↗

Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients.Semantic proximity Read ↗

Immunosenescence increases the rate of acceptance of kidney allotransplants in elderly recipients through exhaustion of CD4+ T-cells.Semantic proximity Read ↗

The Immune Response Against Human Cytomegalovirus Links Cellular to Systemic SenescenceSemantic proximity Read ↗

T Cell Replicative Senescence in Human AgingSemantic proximity Read ↗

Healthy Aging and Latent Infection with CMV Lead to Distinct Changes in CD8+ and CD4+ T-Cell Subsets in the ElderlySemantic proximity Read ↗

The Cytomegalovirus-Specific CD4 + T-Cell Response Expands with Age and Markedly Alters the CD4 + T-Cell RepertoireSemantic proximity Read ↗

Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus InfectionSemantic proximity Read ↗

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term SurvivalSemantic proximity Read ↗

Cytomegalovirus and Epstein-Barr virus co-infected young and middle-aged adults can have an aging-related T-cell phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.