Article
Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses.
Toxins - 3 Apr 2020
Betjes Michiel Gh
Abstract excerpt
Progressive loss of renal function is associated with a series of changes of the adaptive immune system which collectively constitute premature immunological ageing. This phenomenon contributes significantly to the mortality and morbidity of end-stage renal disease (ESRD) patients. In this review, the effect of ESRD on the T cell part of the adaptive immune system is highlighted. Naïve T cell lymphopenia, in...
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