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Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication

27 Jul 2016

Abstract excerpt

UNLABELLED: Ebolavirus (EBOV) is an RNA virus that is known to cause severe hemorrhagic fever in humans and other primates : EBOV successfully enters and replicates in many cell types. This replication is dependent on the virus successfully coopting a number of cellular factors. Many of these factors are currently unidentified but represent potential targets for antiviral therapeutics. Here we show that cellular...

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PMID: 27460797
DOI: 10.1128/mbio.00882-16

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