Article
ALK ambiguous-positive non-small cell lung cancers are tumors challenged by diagnostic and therapeutic issues.
Oncology reports - 1 Sept 2016
Uguen Arnaud, Andrieu-Key Sophie, Vergne Florence, Descourt Renaud, Quéré Gilles, Quintin-Roué Isabelle, Key Stéphane, Guéguen Paul, Talagas Matthieu, De Braekeleer Marc, Marcorelles Pascale
Abstract excerpt
Searching for ALK rearrangements using the approved fluorescent in situ hybridization (FISH) test and complementary immunohistochemistry (IHC) has become the rule to treat patients with advanced non‑small cell lung cancer (NSCLC) with anti‑ALK targeted therapy. The concordance between the two techniques is reported to be strong but imperfect. We report our experience with cases of ALK‑rearranged lung...
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