Article
Adipose Stromal Cells from Visceral and Subcutaneous Fat Facilitate Migration of Ovarian Cancer Cells via IL-6/JAK2/STAT3 Pathway.
Cancer research and treatment - 1 Apr 2017
Kim Boyun, Kim Hee Seung, Kim Soochi, Haegeman Guy, Tsang Benjamin K, Dhanasekaran Danny N, Song Yong Sang
Abstract excerpt
PURPOSE: Adipose stromal cells (ASCs) play an important regulatory role in cancer progression and metastasis by regulating systemic inflammation and tissue metabolism. This study examined whether visceral and subcutaneous ASCs (V- and S-ASCs) facilitate the growth and migration of ovarian cancer cells. MATERIALS AND METHODS: CD45- and CD31- double-negative ASCs were isolated from the subcutaneous and visceral fat...
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