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Article

Determinants of resistance to chemotherapy and ionizing radiation in breast cancer stem cells.

Cancer letters - 1 Oct 2016

Pavlopoulou Athanasia, Oktay Yavuz, Vougas Konstantinos, Louka Maria, Vorgias Constantinos E, Georgakilas Alexandros G

Abstract excerpt

Breast cancer cells are suggested to be organized in a hierarchical manner with a subpopulation of stem cells, termed as breast cancer stem cells (BCSCs), which contribute significantly to tumorigenesis, cancer recurrence and metastasis. BCSCs have been demonstrated to exhibit significant resistance to conventional chemo- and radiotherapy. Recent evidence suggests that treatment of breast cancers with radiation...

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Identifiers

PMID: 27450721
DOI: 10.1016/j.canlet.2016.07.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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