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Article

Familial aggregation and heritability of the melancholic and atypical subtypes of depression.

Journal of affective disorders - 1 Nov 2016

Lamers Femke, Cui Lihong, Hickie Ian B, Roca Catherine, Machado-Vieira Rodrigo, Zarate Carlos A, Merikangas Kathleen R

Abstract excerpt

BACKGROUND: The heterogeneity of mood disorders has been a challenge to our understanding of their underlying biologic and genetic pathways. This report examines the specificity of the familial aggregation of atypical and melancholic subtypes of depression and their clinical correlates in a large community based family study of affective spectrum disorders. METHODS: The sample includes 457 probands and their...

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Identifiers

PMID: 27450632
DOI: 10.1016/j.jad.2016.06.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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