Article
The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length.
Genetics - 1 Sept 2016
Cook Daniel E, Zdraljevic Stefan, Tanny Robyn E, Seo Beomseok, Riccardi David D, Noble Luke M, Rockman Matthew V, Alkema Mark J, Braendle Christian, Kammenga Jan E, Wang John, Kruglyak Leonid, Félix Marie-Anne, Lee Junho, Andersen Erik C
Abstract excerpt
Telomeres are involved in the maintenance of chromosomes and the prevention of genome instability. Despite this central importance, significant variation in telomere length has been observed in a variety of organisms. The genetic determinants of telomere-length variation and their effects on organismal fitness are largely unexplored. Here, we describe natural variation in telomere length across the Caenorhabditis...
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