Article
Common variants of HNF1A gene are associated with diabetic retinopathy and poor glycemic control in normal-weight Japanese subjects with type 2 diabetes mellitus.
Journal of diabetes and its complications - 1 Feb 2017
Morita Kazunori, Saruwatari Junji, Tanaka Takahiro, Oniki Kentaro, Kajiwara Ayami, Miyazaki Hiroko, Yoshida Akira, Jinnouchi Hideaki, Nakagawa Kazuko
Abstract excerpt
AIM: This study investigated the associations between the common hepatocyte nuclear factor-1A (HNF1A) variants and the risk of diabetic retinopathy (DR) in relation to the glycemic control and weight status. METHODS: A retrospective longitudinal analysis was conducted among 354 Japanese patients with type 2 diabetes mellitus (T2DM) (mean follow-up duration: 5.8±2.5 years). The multivariable-adjusted hazard ratio...
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