Article
Genetic variants of nuclear factor erythroid-derived 2-like 2 associated with the complications in Han descents with type 2 diabetes mellitus of Northeast China.
Journal of cellular and molecular medicine - 1 Nov 2016
Xu Xiaohong, Sun Jing, Chang Xiaomin, Wang Ji, Luo Manyu, Wintergerst Kupper A, Miao Lining, Cai Lu
Abstract excerpt
The transcription factor nuclear factor erythroid 2-like 2 (NFE2L2) is essential for preventing type 2 diabetes mellitus (T2DM)-induced complications in animal models. This case and control study assessed genetic variants of NFE2L2 for associations with T2DM and its complications in Han Chinese volunteers. T2DM patients with (n = 214) or without (n = 236) complications, or healthy controls (n = 359), were...
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