Article
KCNN2 polymorphisms and cardiac tachyarrhythmias.
Medicine - 1 Jul 2016
Yu Chih-Chieh, Chia-Ti Tsai, Chen Pei-Lung, Wu Cho-Kai, Chiu Fu-Chun, Chiang Fu-Tien, Chen Peng-Sheng, Chen Chi-Ling, Lin Lian-Yu, Juang Jyh-Ming, Ho Li-Ting, Lai Ling-Ping, Yang Wei-Shiung, Lin Jiunn-Lee
Abstract excerpt
Potassium calcium-activated channel subfamily N member 2 (KCNN2) encodes an integral membrane protein that forms small-conductance calcium-activated potassium (SK) channels. Recent studies in animal models show that SK channels are important in atrial and ventricular repolarization and arrhythmogenesis. However, the importance of SK channels in human arrhythmia remains unclear. The purpose of the present study...
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