Article
Case report of a Li-Fraumeni syndrome-like phenotype with a de novo mutation in CHEK2.
Medicine - 1 Jul 2016
Zhuang Xuehan, Li Yongping, Cao Hongzhi, Wang Ting, Chen Jianghao, Liu Jiayun, Lin Liya, Ye Rui, Li Xinyang, Liu Shuang, Li Weiyang, Lv Yonggang, Zhang Juliang, He Chenyang, Xu Xun, Wang Zhen, Huang Chen, Liu Xiao, Wang Ling
Abstract excerpt
BACKGROUND: Cases of multiple tumors are rarely reported in China. In our study, a 57-year-old female patient had concurrent squamous cell carcinoma, mucoepidermoid carcinoma, brain cancer, bone cancer, and thyroid cancer, which has rarely been reported to date. METHODS: To determine the relationship among these multiple cancers, available DNA samples from the thyroid, lung, and skin tumors and from normal...
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