Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy.

doi:10.1038/nrd3628

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Article

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy.

Nature reviews. Drug discovery - 1 Feb 2012

Millan Mark J, Agid Yves, Brüne Martin, Bullmore Edward T, Carter Cameron S, Clayton Nicola S, Connor Richard, Davis Sabrina, Deakin Bill, DeRubeis Robert J, Dubois Bruno, Geyer Mark A, Goodwin Guy M, Gorwood Philip, Jay Thérèse M, Joëls Marian, Mansuy Isabelle M, Meyer-Lindenberg Andreas, Murphy Declan, Rolls Edmund, Saletu Bernd, Spedding Michael, Sweeney John, Whittington Miles, Young Larry J

Abstract excerpt

Studies of psychiatric disorders have traditionally focused on emotional symptoms such as depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are equally prominent and severely compromise quality of life, including social and professional integration. Consequently, intensive efforts are being made to characterize the cellular and cerebral circuits underpinning cognitive function,...

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PMID: 22293568
DOI: 10.1038/nrd3628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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