Article
Cross-reactivity profiles of hybrid capture II, cobas, and APTIMA human papillomavirus assays: split-sample study.
BMC cancer - 20 Jul 2016
Preisler Sarah, Rebolj Matejka, Ejegod Ditte Møller, Lynge Elsebeth, Rygaard Carsten, Bonde Jesper
Abstract excerpt
BACKGROUND: High-risk Human Papillomavirus (HPV) testing is replacing cytology in cervical cancer screening as it is more sensitive for preinvasive cervical lesions. However, the bottleneck of HPV testing is the many false positive test results (positive tests without cervical lesions). Here, we evaluated to what extent these can be explained by cross-reactivity, i.e. positive test results without evidence of...
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