Article
Transition from Hybrid Capture 2 to Cobas 4800 in Hpv detection: sensitivity and specificity for Cin2+ in two time periods.
Infectious diseases (London, England) - 1 Jul 2018
Bottari Fabio, Boveri Sara, Iacobone Anna Daniela, Gulmini Chiara, Igidbashian Sarah, Cassatella Maria Cristina, Landoni Fabio, Sandri Maria Teresa
Abstract excerpt
BACKGROUND: High-risk (HR) Human Papilloma Virus (HPV) Tests for HPV detection differ in sensitivity and specificity. In this study, we evaluated the sensitivity and specificity of the HC2 HR HPV Test and the Cobas 4800 HPV Test in consecutive cervical samples collected from a referral population with a high prevalence of disease, using CIN2+ histology as clinical outcome. METHODS: Ten thousand two-hundred and...
Topics
- Cervix Uteri
- Cytological Techniques
- DNA, Viral
- Early Detection of Cancer
- Female
- Genotype
- Humans
- Molecular Diagnostic Techniques
- Papillomaviridae
- Papillomavirus Infections
- Reagent Kits, Diagnostic
- Sensitivity and Specificity