Performance of the HPV E6/E7 mRNA Aptima HPV assay combined with partial genotyping compared with the HPV DNA Cobas 4800 HPV test for use in primary screening: Results from the CERVIVA HPV primary screening study in Ireland.

doi:10.1002/ijc.34685

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Performance of the HPV E6/E7 mRNA Aptima HPV assay combined with partial genotyping compared with the HPV DNA Cobas 4800 HPV test for use in primary screening: Results from the CERVIVA HPV primary screening study in Ireland.

International journal of cancer - 1 Jan 2024

White Christine, Reynolds Stephen, Murphy Katherine, Keegan Helen, Naik Padma, O'Brien Roisin, Pilkington Loretto, Sharkey Ochoa Imogen, Glesson Grainne, Russell Noirin, Nuttall David, Tewari Prerna, Wright Fiona, O'Toole Sharon, Sharp Linda, Flannelly Grainne, O'Leary John J, Martin Cara M

Abstract excerpt

There are currently several validated HPV tests. However, longitudinal data which spans appropriate age ranges, as well as evaluation of potential screening algorithms are necessary for screening programmes choice of test. The objective of our study was to evaluate the performance of HPV mRNA and HPV DNA testing, including partial genotyping, in routine cervical screening. As part of the CERVIVA HPV Primary...

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PMID: 37632406
DOI: 10.1002/ijc.34685

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