Article
Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals.
JAMA cardiology - 1 Jul 2016
Roberts Jason D, Hu Donglei, Heckbert Susan R, Alonso Alvaro, Dewland Thomas A, Vittinghoff Eric, Liu Yongmei, Psaty Bruce M, Olgin Jeffrey E, Magnani Jared W, Huntsman Scott, Burchard Esteban G, Arking Dan E, Bibbins-Domingo Kirsten, Harris Tamara B, Perez Marco V, Ziv Elad, Marcus Gregory M
Abstract excerpt
IMPORTANCE: White persons have a higher risk of atrial fibrillation (AF) compared with black individuals despite a lower prevalence of risk factors. This difference may be due, at least in part, to genetic factors. OBJECTIVES: To determine whether 9 single-nucleotide polymorphisms (SNPs) associated with AF account for this paradoxical differential racial risk for AF and to use admixture mapping to search...
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