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Article

Structural basis of Zika virus helicase in recognizing its substrates

18 Jul 2016

Abstract excerpt

The recent explosive outbreak of Zika virus (ZIKV) infection has been reported in South and Central America and the Caribbean. Neonatal microcephaly associated with ZIKV infection has already caused a public health emergency of international concern. No specific vaccines or drugs are currently available to treat ZIKV infection. The ZIKV helicase, which plays a pivotal role in viral RNA replication, is an...

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PMID: 27430951
DOI: 10.1007/s13238-016-0293-2

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