Article
Parishin from Gastrodia elata Extends the Lifespan of Yeast via Regulation of Sir2/Uth1/TOR Signaling Pathway.
Oxidative medicine and cellular longevity - 1 Jan 2016
Lin Yanfei, Sun Yujuan, Weng Yufang, Matsuura Akira, Xiang Lan, Qi Jianhua
Abstract excerpt
Parishin is a phenolic glucoside isolated from Gastrodia elata, which is an important traditional Chinese medicine; this glucoside significantly extended the replicative lifespan of K6001 yeast at 3, 10, and 30 μM. To clarify its mechanism of action, assessment of oxidative stress resistance, superoxide dismutase (SOD) activity, malondialdehyde (MDA), and reactive oxygen species (ROS) assays, replicative...
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