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Article

[Afatinib in patients with squamous cell carcinoma of the lung: current context and the option of oral treatment].

Medicina clinica - 1 Apr 2016

Cobo Manuel, Gutiérrez Vanesa, Rodelo Luis, López Omar, Ruiz María, Godoy Ana

Abstract excerpt

Squamous cell carcinoma (SCC) of the lung represents 30% of non-small cell lung cancers (NSCLC). Docetaxel and the EGFR tyrosine kinase inhibitor (TKI), erlotinib, are the only two drugs approved for second-line treatment of advanced SCC. The sensitivity of SCC to TKIs can be explained by EGFR overexpression. Erlotinib demonstrated a significant benefit in terms of overall survival (OS) in successive lines in...

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Share to Administration, Oral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Carcinoma, Squamous Cell

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Source

Identifiers

PMID: 27426245
DOI: 10.1016/S0025-7753(16)30260-3

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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