Article
Afatinib: A first-line treatment for selected patients with metastatic non-small-cell lung cancer.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists - 15 Nov 2014
Engle Jeff A, Kolesar Jill M
Abstract excerpt
PURPOSE: The pharmacology, pharmacokinetics, clinical efficacy, safety, adverse effects, dosage and administration, and role in therapy of afatinib in the management of non-small-cell lung cancer (NSCLC) are reviewed. SUMMARY: Afatinib (Gilotrif, Boehringer Ingelheim) is a novel oral tyrosine kinase inhibitor (TKI) recently approved for the first-line treatment of patients with NSCLC whose tumors are driven by...
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