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Article

Long-term response to second-line afatinib treatment for advanced squamous cell carcinoma non-small cell lung cancer: a rare case report.

The Journal of international medical research - 1 Oct 2020

Sun Mengyao, Guo Ye, Wang Xu, Sun Chao, Shao Jiangbo, Xu Yinghui, Qiu Shi, Ma Kewei

Abstract excerpt

The ErbB family is composed of four cell membrane receptors: ErbB-1 (epidermal growth factor receptor or human epidermal growth factor receptor [HER]1), ErbB-2 (HER2), ErbB-3 (HER3), and ErbB-4 (HER4). All members of the ErbB family play a critical role in regulating cell growth, proliferation and migration of tumours. Afatinib is an irreversible ErbB family inhibitor that is approved for second-line treatment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33115309
DOI: 10.1177/0300060520964700
PMCID: PMC7780586

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