Article
The safety of afatinib for the treatment of non-small cell lung cancer.
Expert opinion on drug safety - 1 Nov 2016
Barron Feliciano, de la Torre-Vallejo Martha, Luna-Palencia Rosa Luz, Cardona Andres F, Arrieta Oscar
Abstract excerpt
INTRODUCTION: Lung cancer tumors present EGFR mutations associated with an increased response rate to tyrosine kinase inhibitors (TKIs). Afatinib acts as an irreversible pan-ErbB-TKI. Areas covered: This review summarizes the results of clinical trials in NSCLC regarding its safety and efficacy. Expert opinion: Afatinib in 40 mg doses is highly effective in patients with NSCLC and EGFR mutations, improving...
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