Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of Hispanic BRCA1 and BRCA2 mutations among hereditary breast and ovarian cancer patients from Brazil reveals differences among Latin American populations.

Cancer genetics - 1 Sept 2016

Alemar Bárbara, Herzog Josef, Brinckmann Oliveira Netto Cristina, Artigalás Osvaldo, Schwartz Ida Vanessa D, Matzenbacher Bittar Camila, Ashton-Prolla Patricia, Weitzel Jeffrey N

Abstract excerpt

Germline mutations in BRCA1 or BRCA2 (BRCA) are responsible for 5-15% of breast (BC) and ovarian cancers (OC), predisposing to the development of early onset and often multiple primary tumors. Since mutation carriers can benefit from risk-reducing interventions, the identification of individuals with hereditary breast and ovarian cancer (HBOC) syndrome has a significant clinical impact. We assessed whether a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Hispanic or Latino

Share to Mutation

Share to Ovarian Neoplasms

Share to Young Adult

Source

Identifiers

PMID: 27425403
DOI: 10.1016/j.cancergen.2016.06.008

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of Hispanic BRCA1 and BRCA2 mutations among hereditary breast and ovarian cancer patients from Brazil reveals differences among Latin American populations.PMID 27425403Read ↗

Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry.Semantic proximity Read ↗

The spectrum of BRCA1 and BRCA2 alleles in Latin America and the Caribbean: a clinical perspective.Semantic proximity Read ↗

Germline molecular data in hereditary breast cancer in Brazil: Lessons from a large single-center analysis.Semantic proximity Read ↗

BRCA1 and BRCA2 mutational profile and prevalence in hereditary breast and ovarian cancer (HBOC) probands from Southern Brazil: Are international testing criteria appropriate for this specific population?Semantic proximity Read ↗

A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer.Semantic proximity Read ↗

High proportion of BRCA1/2 founder mutations in Hispanic breast/ovarian cancer families from ColombiaSemantic proximity Read ↗

Genetic epidemiology of BRCA1- and BRCA2-associated cancer across Latin AmericaSemantic proximity Read ↗

Germline Pathogenic Variant Prevalence Among Latin American and US Hispanic Individuals Undergoing Testing for Hereditary Breast and Ovarian Cancer: A Cross-Sectional StudySemantic proximity Read ↗

Systematic review of the molecular basis of hereditary breast and ovarian cancer syndrome in Brazil: the current scenario.Semantic proximity Read ↗

Identification of the prevalent BRCA1 and BRCA2 mutations in the female population of Puerto Rico.Semantic proximity Read ↗

BRCA1 and BRCA2 germline mutation analysis from a cohort of 1267 patients at high risk for breast cancer in Brazil.Semantic proximity Read ↗

Access disparities and underutilization of germline genetic testing in Chilean breast cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.