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Article

Matched and mixed cap derivatives in the tetracyclic indole class of HCV NS5A inhibitors.

Bioorganic & medicinal chemistry letters - 15 Aug 2016

Dwyer Michael P, Keertikar Kerry M, Chen Lei, Tong Ling, Selyutin Oleg, Nair Anilkumar G, Yu Wensheng, Zhou Guowei, Lavey Brian J, Yang De-Yi, Wong Michael, Kim Seong Heon, Coburn Craig A, Rosenblum Stuart B, Zeng Qingbei, Jiang Yueheng, Shankar Bandarpalle B, Rizvi Razia, Nomeir Amin A, Liu Rong, Agrawal Sony, Xia Ellen, Kong Rong, Zhai Ying, Ingravallo Paul, Asante-Appiah Ernest, Kozlowski Joseph A

Abstract excerpt

A matched and mixed capping SAR study was conducted on the tetracyclic indole class of HCV NS5A inhibitors to examine the influence of modifications of this region on the overall HCV virologic resistance profiles.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27423481
DOI: 10.1016/j.bmcl.2016.06.063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27423481-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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