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Article

Investigating intra-host and intra-herd sequence diversity of foot-and-mouth disease virus.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2016

King David J, Freimanis Graham L, Orton Richard J, Waters Ryan A, Haydon Daniel T, King Donald P

Abstract excerpt

Due to the poor-fidelity of the enzymes involved in RNA genome replication, foot-and-mouth disease (FMD) virus samples comprise of unique polymorphic populations. In this study, deep sequencing was utilised to characterise the diversity of FMD virus (FMDV) populations in 6 infected cattle present on a single farm during the series of outbreaks in the UK in 2007. A novel RT-PCR method was developed to amplify a...

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Identifiers

PMID: 27421209
DOI: 10.1016/j.meegid.2016.07.010
PMCID: PMC5036933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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