Article
The impact of within-herd genetic variation upon inferred transmission trees for foot-and-mouth disease virus.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2015
Valdazo-González Begoña, Kim Jan T, Soubeyrand Samuel, Wadsworth Jemma, Knowles Nick J, Haydon Daniel T, King Donald P
Abstract excerpt
Full-genome sequences have been used to monitor the fine-scale dynamics of epidemics caused by RNA viruses. However, the ability of this approach to confidently reconstruct transmission trees is limited by the knowledge of the genetic diversity of viruses that exist within different epidemiological units. In order to address this question, this study investigated the variability of 45 foot-and-mouth disease virus...
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