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Article

Immunoregulatory Role of HLA-G in Allergic Diseases.

Journal of immunology research - 1 Jan 2016

Murdaca Giuseppe, Contini Paola, Negrini Simone, Ciprandi Giorgio, Puppo Francesco

Abstract excerpt

Allergic diseases are sustained by a T-helper 2 polarization leading to interleukin-4 secretion, IgE-dependent inflammation, and mast cell and eosinophil activation. HLA-G molecules, both in membrane-bound and in soluble forms, play a central role in modulation of immune responses. Elevated levels of soluble HLA-G (sHLA-G) molecules are detected in serum of patients with allergic rhinitis to seasonal and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27413762
DOI: 10.1155/2016/6865758
PMCID: PMC4931064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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