Article
A genome-wide association meta-analysis on apolipoprotein A-IV concentrations.
Human molecular genetics - 15 Aug 2016
Lamina Claudia, Friedel Salome, Coassin Stefan, Rueedi Rico, Yousri Noha A, Seppälä Ilkka, Gieger Christian, Schönherr Sebastian, Forer Lukas, Erhart Gertraud, Kollerits Barbara, Marques-Vidal Pedro, Ried Janina, Waeber Gerard, Bergmann Sven, Dähnhardt Doreen, Stöckl Andrea, Kiechl Stefan, Raitakari Olli T, Kähönen Mika, Willeit Johann, Kedenko Ludmilla, Paulweber Bernhard, Peters Annette, Meitinger Thomas, Strauch Konstantin, Lehtimäki Terho, Hunt Steven C, Vollenweider Peter, Kronenberg Florian
Abstract excerpt
Apolipoprotein A-IV (apoA-IV) is a major component of HDL and chylomicron particles and is involved in reverse cholesterol transport. It is an early marker of impaired renal function. We aimed to identify genetic loci associated with apoA-IV concentrations and to investigate relationships with known susceptibility loci for kidney function and lipids. A genome-wide association meta-analysis on apoA-IV...
Topics
- Alleles
- Apolipoproteins A
- Cholesterol, HDL
- Female
- Genome-Wide Association Study
- Humans
- Kidney
- Lipids