Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae.

PloS one - 1 Jan 2013

Mahdi Layla K, Ebrahimie Esmaeil, Adelson David L, Paton James C, Ogunniyi Abiodun D

Abstract excerpt

To date, the role of transcription factors (TFs) in the progression of disease for many pathogens is yet to be studied in detail. This is probably due to transient, and generally low expression levels of TFs, which are the central components controlling the expression of many genes during the course of infection. However, a small change in the expression or specificity of a TF can radically alter gene expression....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Host-Pathogen Interactions

Share to Organ Specificity

Share to Pneumococcal Infections

Share to Streptococcus pneumoniae

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 23967124
DOI: 10.1371/journal.pone.0070862
PMCID: PMC3742648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae.PMID 23967124Read ↗

From nose to lung: the regulation behind Streptococcus pneumoniae virulence factorsSemantic proximity Read ↗

Molecular pathogenesis of pneumococcal pneumoniaSemantic proximity Read ↗

Pneumococcal metabolic adaptation and colonization is regulated by the two-component regulatory system 08Semantic proximity Read ↗

Comparative transcriptional profiling of the lung reveals shared and distinct features of Streptococcus pneumoniae and influenza A virus infection.Semantic proximity Read ↗

Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen–host interactionsSemantic proximity Read ↗

Streptococcus pyogenes (“Group A Streptococcus”), a Highly Adapted Human Pathogen—Potential Implications of Its Virulence Regulation for Epidemiology and Disease ManagementSemantic proximity Read ↗

Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors.Semantic proximity Read ↗

The variome of pneumococcal virulence factors and regulators.Semantic proximity Read ↗

An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.Semantic proximity Read ↗

Identification of Genes That Contribute to the Pathogenesis of Invasive Pneumococcal Disease by In Vivo Transcriptomic AnalysisSemantic proximity Read ↗

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.Semantic proximity Read ↗

Transcriptome studies on Streptococcus pneumoniae, illustration of early response genes to THP-1 human macrophages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.