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Article

Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan.

Antimicrobial agents and chemotherapy - 1 Jun 2004

Sanbongi Yumiko, Ida Takashi, Ishikawa Midori, Osaki Yumi, Kataoka Hiroshi, Suzuki Takahisa, Kondo Kumiko, Ohsawa Fukuichi, Yonezawa Minoru

Abstract excerpt

All six penicillin-binding protein (PBP) genes, namely, pbp1a, pbp1b, pbp2a, pbp2b, pbp2x, and pbp3, of 40 Streptococcus pneumoniae clinical isolates, including penicillin-resistant S. pneumoniae isolates collected in Japan, were completely sequenced. The MICs of penicillin for these strains varied between 0.015 and 8 microg/ml. In PBP 2X, the Thr550Ala mutation close to the KSG motif was observed in only 1 of 40...

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Identifiers

PMID: 15155228
DOI: 10.1128/AAC.48.6.2244-2250.2004
PMCID: PMC415593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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