Article
Genetic and Clinical Predictive Factors of Sulfonylurea Failure in Patients with Type 2 Diabetes.
Diabetes technology & therapeutics - 1 Sept 2016
Ren Qian, Xiao Di, Han Xueyao, Edwards Stacey L, Wang Huaiqing, Tang Yong, Zhang Simin, Li Xi, Zhang Xiuying, Cai Xiaoling, Liu Zhaoqian, Paul Sanjoy K, Ji Linong
Abstract excerpt
BACKGROUND: Sulfonylureas are widely used to treat type 2 diabetes (T2DM). Although genetic variations are associated with sulfonylurea treatment responses in T2DM patients, whether these variations can be used to predict heterogeneous treatment responses is unclear. In this study, we assessed the potential utility of combining information from multiple variants and phenotypes to predict sulfonylurea response....
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