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Pharmacogenomics of Oral Antidiabetic Medications: Current Data and Pharmacoepigenomic Perspective

1 Aug 2011

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is an increasingly prevalent disease. Several classes of drugs are currently available to treat T2DM patients; however, clinical response to these drugs often exhibits significant variation among individuals. For the oral antidiabetic drug classes of sulfonylureas, nonsulfonylurea insulin secretagogs, biguanides and thiazolidinediones, pharmacogenomic evidence has accumulated...

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PMID: 21843065
DOI: 10.2217/pgs.11.65

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