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Article

Role of epistasis on the fixation probability of a non-mutator in an adapted asexual population.

Journal of theoretical biology - 21 Oct 2016

James Ananthu

Abstract excerpt

The mutation rate of a well adapted population is prone to reduction so as to have a lower mutational load. We aim to understand the role of epistatic interactions between the fitness affecting mutations in this process. Using a multitype branching process, the fixation probability of a single non-mutator emerging in a large asexual mutator population is analytically calculated here. The mutator population...

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Share to Adaptation, Physiological
Share to Epistasis, Genetic
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Probability

Share to Reproducibility of Results

Share to Reproduction, Asexual

Share to Selection, Genetic

Share to Stochastic Processes

Source

Identifiers

PMID: 27401675
DOI: 10.1016/j.jtbi.2016.07.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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