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Article

Fixation of mutators in asexual populations: the role of genetic drift and epistasis.

Evolution; international journal of organic evolution - 1 Apr 2013

Jain Kavita, Nagar Apoorva

Abstract excerpt

We study the evolutionary dynamics of an asexual population of nonmutators and mutators on a class of epistatic fitness landscapes. We consider the situation in which all mutations are deleterious and mutators are produced from nonmutators continually at a constant rate. We find that in an infinitely large population, a minimum nonmutator-to-mutator conversion rate is required to fix the mutators but an...

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Source

Identifiers

PMID: 23550762
DOI: 10.1111/evo.12005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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