Article
Impact of gross total resection in patients with WHO grade III glioma harboring the IDH 1/2 mutation without the 1p/19q co-deletion.
Journal of neuro-oncology - 1 Sept 2016
Kawaguchi Tomohiro, Sonoda Yukihiko, Shibahara Ichiyo, Saito Ryuta, Kanamori Masayuki, Kumabe Toshihiro, Tominaga Teiji
Abstract excerpt
The prognosis of patients with WHO grade III gliomas is highly dependent on their genomic status such as the isocitrate dehydrogenase (IDH) 1/2 mutation and1p/19q co-deletion. However, difficulties have been associated with determining which tumors have certain genomic profiles by preoperative radiographical modalities, and the role of surgical resection in achieving better outcomes remains unclear. This...
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