Article
Association and interaction of PPARα, δ, and γ gene polymorphisms with low-density lipoprotein-cholesterol in a Chinese Han population.
Genetic testing and molecular biomarkers - 1 Jul 2015
Fan Wei, Shen Chao, Wu Ming, Zhou Zheng-Yuan, Guo Zhi-Rong
Abstract excerpt
AIMS: Elevated low-density lipoprotein-cholesterol (LDL-C) is regarded as one of major risks of cardiovascular diseases and atherosclerotic events. It has been previously reported that peroxisome proliferator-activated receptors (PPARs) play an important role in the regulation of lipid metabolism. In this study, we aimed to investigate the influence of PPARα/δ/γ gene polymorphisms on LDL-C level. Eight hundred...
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