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Article

Genetic evidence for the association of the hypothalamic-pituitary-adrenal (HPA) axis with ADHD and methylphenidate treatment response.

Neuromolecular medicine - 1 Mar 2013

Fortier Marie-Ève, Sengupta Sarojini M, Grizenko Natalie, Choudhry Zia, Thakur Geeta, Joober Ridha

Abstract excerpt

Exposure to stressors results in a spectrum of autonomic, endocrine, and behavioral responses. A key pathway in this response to stress is the hypothalamic-pituitary-adrenal (HPA) axis, which results in a transient increase in circulating cortisol, which exerts its effects through the two related ligand-activated transcription factors: the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR). Genetic...

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Identifiers

PMID: 23055001
DOI: 10.1007/s12017-012-8202-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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