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Article

Predicting attention-deficit/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach.

Translational psychiatry - 6 Jun 2017

van der Meer D, Hoekstra P J, van Donkelaar M, Bralten J, Oosterlaan J, Heslenfeld D, Faraone S V, Franke B, Buitelaar J K, Hartman C A

Abstract excerpt

Identifying genetic variants contributing to attention-deficit/hyperactivity disorder (ADHD) is complicated by the involvement of numerous common genetic variants with small effects, interacting with each other as well as with environmental factors, such as stress exposure. Random forest regression is well suited to explore this complexity, as it allows for the analysis of many predictors simultaneously, taking...

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Source

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Identifiers

PMID: 28585928
DOI: 10.1038/tp.2017.114
PMCID: PMC5537639

Genes

DRD4
ESR1
GABRA6
NPSR1
PER3
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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