Contemplating Bretscher's View that the Tritope Model is 'Implausible'.

doi:10.1111/sji.12458

Back to search

Article

Contemplating Bretscher's View that the Tritope Model is 'Implausible'.

Scandinavian journal of immunology - 1 Sept 2016

Cohn M

Abstract excerpt

There is, at present, only two models of the TCR structure-function relationship. These are referred to here as the Standard (Centric) model and the Tritope model. While I have argued that the Standard model is untenable and proposed the Tritope to replace it, Bretscher has argued that the Tritope model is 'implausible' and throws his support for the Standard model. This essay analyses the implausibility argument...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protein Isoforms

Share to Receptors, Antigen, B-Cell

Share to Receptors, Antigen, T-Cell

Share to Signal Transduction

Share to Structural Homology, Protein

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 8 closest

Contemplating Bretscher's View that the Tritope Model is 'Implausible'.PMID 27391579Read

An observation that illustrates most T cell receptor structure-function relationships.Semantic proximity Read

[Structure and function of TCR].Semantic proximity Read

TZAP or not to zap telomeres.Semantic proximity Read

Getting a grip on Thy-1 signalingSemantic proximity Read

Branching out to gain control: how the pre-TCR is linked to multiple functions.Semantic proximity Read

Biochemistry. KSR plays CRAF-ty.Semantic proximity Read

Regulatory circuits of T cell function in cancerSemantic proximity Read

T Cell Activation Machinery: Form and Function in Natural and Engineered Immune ReceptorsSemantic proximity Read