Article
Development and evaluation of a non-ribosomal random PCR and next-generation sequencing based assay for detection and sequencing of hand, foot and mouth disease pathogens.
Virology journal - 7 Jul 2016
Nguyen Anh To, Tran Thanh Tan, Hoang Van Minh Tu, Nghiem Ngoc My, Le Nhu Nguyen Truc, Le Thanh Thi My, Phan Qui Tu, Truong Khanh Huu, Le Nhan Nguyen Thanh, Ho Viet Lu, Do Viet Chau, Ha Tuan Manh, Nguyen Hung Thanh, Nguyen Chau Van Vinh, Thwaites Guy, van Doorn H Rogier, Le Tan Van
Abstract excerpt
BACKGROUND: Hand, foot and mouth disease (HFMD) has become a major public health problem across the Asia-Pacific region, and is commonly caused by enterovirus A71 (EV-A71) and coxsackievirus A6 (CV-A6), CV-A10 and CV-A16. Generating pathogen whole-genome sequences is essential for understanding their evolutionary biology. The frequent replacements among EV serotypes and a limited numbers of available whole-genome...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.