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Article

Rapid detection of hand, foot and mouth disease enterovirus genotypes by multiplex PCR.

Journal of virological methods - 1 Aug 2018

Wang Min, Ren Qian, Zhang Zhenjie, Zhang Lehai, Carr Michael J, Li Juan, Zhou Hong, Shi Weifeng

Abstract excerpt

Hand, foot and mouth disease (HFMD) is a pediatric disease associated with infection by enterovirus (EV) genotypes. The major HFMD EV pathogens are enterovirus A71 (EVA71) and coxsackievirus A16 (CVA16); however, recently, coxsackievirus A6 (CVA6) and coxsackievirus A10 (CVA10) have also emerged. EV genotypes cannot be distinguished on clinical grounds and a new methodology for the rapid detection of the four...

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PMID: 29758237
DOI: 10.1016/j.jviromet.2018.05.005

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