Article
The Relationship Between Glutathione S-Transferase-P1 and Beta-2 Adrenoreceptor Genotypes with Asthmatic Patients in the Turkish Population.
Genetic testing and molecular biomarkers - 1 Sept 2016
Kaymak Cetin, Aygun Kocabas Neslihan, Aydın Nesrin, Oztuna Derya, Karakaya Ali Esat
Abstract excerpt
BACKGROUND: Individual differences in the activity of enzymes that metabolize xenobiotics can impact health and disease. Beta-2 adrenoreceptor (ADRB2) is a functional G-coupled protein expressed in the vascular endothelium of lungs, alveolar walls, and the ganglions of cholinergic nerves which induces bronchodilation in response to catecholamines. Glutathione S-Transferase-P1 (GSTP1) is a candidate pi class GST...
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