Article
Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease.
Scientific reports - 6 Jul 2016
Muenchhoff Julia, Poljak Anne, Thalamuthu Anbupalam, Gupta Veer B, Chatterjee Pratishtha, Raftery Mark, Masters Colin L, Morris John C, Bateman Randall J, Fagan Anne M, Martins Ralph N, Sachdev Perminder S
Abstract excerpt
The autosomal dominant form of Alzheimer's disease (ADAD) is far less prevalent than late onset Alzheimer's disease (LOAD), but enables well-informed prospective studies, since symptom onset is near certain and age of onset is predictable. Our aim was to discover plasma proteins associated with early AD pathology by investigating plasma protein changes at the asymptomatic and symptomatic stages of ADAD....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.